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Heroin is one of the most dangerous drugs out there. Arguably the most physically addictive illicit drug, heroin carries with it serious consequences when abused. The effects on one's appearance are bad enough, ranging from drastic weight loss to decaying teeth. The long-term effects, however, are much more dangerous. Abuse heroin on a regular basis and the chances of suffering from kidney and liver disease, cardiovascular problems, and dying from an accidental overdose become so much higher.