The greatest danger from mixing other drugs with amphetamines is additional strain on the heart and increased blood pressure. Be careful.
Please note that there have been very few scientific studies into the effects of combining psychoactive drugs. The information presented here is anecdotal. It is based on the subjective reports of experienced users. Different people will respond differently to different drugs and drug combination. Know your body.
alcohol Allows extended binge drinking. Increases likelihood of aggressive / irresponsible behavior. Not good for liver and kidneys. Terrible hangover.
cocaine unlikely combination as the effects are so similar, danger of increased toxicity and strain on heart
ecstasy extends E experience, increased energy and euphoria, but also strain on heart and risk of over-heating. Moderation recommended.
ghb no information on mixing gamma-Hydroxybutyric acid with amphetamines available - can you help?
heroin surprisingly common among heavy speed users as heroin provides physical grounding to speed's more psychotic tendencies
ketamine fast and slow, leading to intense Matrix-like perception of time changes - no increased health risks
LSD has its own speedy effect
marijuana can take the edge off the buzz
mushrooms increased weirdness; energizing; paranoia usually increased; comedown can be rocky
tobacco speeding smokers usually smoke more cigarettes, usual perils of tobacco apply
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